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DNA Methylation of TGFβ Target Genes: Epigenetic Control of TGFβ Functional Duality in Liver Cancer

Transforming growth factor beta (TGFβ) plays a key role in liver carcinogenesis. However, its action is complex, since TGFβ exhibits tumor-suppressive or oncogenic properties, depending on the tumor stage. At an early stage TGFβ exhibits cytostatic features, but at a later stage it promotes cell gro...

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Detalles Bibliográficos
Autores principales: Bévant, Kevin, Desoteux, Matthis, Abdel Wahab, Abdel Hady A., Abdel Wahab, Sabrin A., Metwally, Ayman Mohamed, Coulouarn, Cédric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468746/
https://www.ncbi.nlm.nih.gov/pubmed/34571856
http://dx.doi.org/10.3390/cells10092207