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The Role of Drosophila CtIP in Homology-Directed Repair of DNA Double-Strand Breaks

DNA double-strand breaks (DSBs) are a particularly genotoxic type of DNA damage that can result in chromosomal aberrations. Thus, proper repair of DSBs is essential to maintaining genome integrity. DSBs can be repaired by non-homologous end joining (NHEJ), where ends are processed before joining thr...

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Detalles Bibliográficos
Autores principales: Yannuzzi, Ian, Butler, Margaret A., Fernandez, Joel, LaRocque, Jeannine R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468788/
https://www.ncbi.nlm.nih.gov/pubmed/34573412
http://dx.doi.org/10.3390/genes12091430