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Targeting the p53 Pathway in CLL: State of the Art and Future Perspectives

SIMPLE SUMMARY: The p53 pathway plays a fundamental role in preventing the accumulation of unrepaired DNA damage. Unsurprisingly, cancer cells often break this protective barrier by inactivating either p53 itself or other proteins along this pathway, such as ATM. This facilitates the acquisition of...

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Detalles Bibliográficos
Autores principales: Kwok, Marwan, Agathanggelou, Angelo, Davies, Nicholas, Stankovic, Tatjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468925/
https://www.ncbi.nlm.nih.gov/pubmed/34572908
http://dx.doi.org/10.3390/cancers13184681