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Targeting the p53 Pathway in CLL: State of the Art and Future Perspectives
SIMPLE SUMMARY: The p53 pathway plays a fundamental role in preventing the accumulation of unrepaired DNA damage. Unsurprisingly, cancer cells often break this protective barrier by inactivating either p53 itself or other proteins along this pathway, such as ATM. This facilitates the acquisition of...
Autores principales: | Kwok, Marwan, Agathanggelou, Angelo, Davies, Nicholas, Stankovic, Tatjana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468925/ https://www.ncbi.nlm.nih.gov/pubmed/34572908 http://dx.doi.org/10.3390/cancers13184681 |
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