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The Role of Dupilumab in Severe Asthma

Dupilumab is a fully humanized monoclonal antibody, capable of inhibiting intracellular signaling of both interleukin (IL)-4 and IL-13. These are two molecules that, together with other proinflammatory cytokines such as IL-5 and eotaxins, play a pivotal role in orchestrating the airway inflammatory...

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Detalles Bibliográficos
Autores principales: Ricciardolo, Fabio Luigi Massimo, Bertolini, Francesca, Carriero, Vitina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468984/
https://www.ncbi.nlm.nih.gov/pubmed/34572281
http://dx.doi.org/10.3390/biomedicines9091096