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The Role of Dupilumab in Severe Asthma
Dupilumab is a fully humanized monoclonal antibody, capable of inhibiting intracellular signaling of both interleukin (IL)-4 and IL-13. These are two molecules that, together with other proinflammatory cytokines such as IL-5 and eotaxins, play a pivotal role in orchestrating the airway inflammatory...
Autores principales: | Ricciardolo, Fabio Luigi Massimo, Bertolini, Francesca, Carriero, Vitina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468984/ https://www.ncbi.nlm.nih.gov/pubmed/34572281 http://dx.doi.org/10.3390/biomedicines9091096 |
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