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Exacerbated Age-Related Hippocampal Alterations of Microglia Morphology, β-Amyloid and Lipofuscin Deposition and Presenilin Overexpression in Per1(−/−)-Mice

In humans, alterations of circadian rhythms and autophagy are linked to metabolic, cardiovascular and neurological dysfunction. Autophagy constitutes a specific form of cell recycling in many eukaryotic cells. Aging is the principal risk factor for the development of neurodegenerative diseases. Thus...

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Detalles Bibliográficos
Autores principales: Börner, Jan Hendrik, Rawashdeh, Oliver, Rami, Abdelhaq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469021/
https://www.ncbi.nlm.nih.gov/pubmed/34572962
http://dx.doi.org/10.3390/antiox10091330