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Activated Histone Acetyltransferase p300/CBP-Related Signalling Pathways Mediate Up-Regulation of NADPH Oxidase, Inflammation, and Fibrosis in Diabetic Kidney

Accumulating evidence implicates the histone acetylation-based epigenetic mechanisms in the pathoetiology of diabetes-associated micro-/macrovascular complications. Diabetic kidney disease (DKD) is a progressive chronic inflammatory microvascular disorder ultimately leading to glomerulosclerosis and...

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Detalles Bibliográficos
Autores principales: Lazar, Alexandra-Gela, Vlad, Mihaela-Loredana, Manea, Adrian, Simionescu, Maya, Manea, Simona-Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469026/
https://www.ncbi.nlm.nih.gov/pubmed/34572988
http://dx.doi.org/10.3390/antiox10091356