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Analgesic and Anti-Inflammatory Effects of the Synthetic Neurosteroid Analogue BNN27 during CFA-Induced Hyperalgesia

Dehydroepiandrosterone (DHEA), an adrenal and neurosteroid hormone with strong neuroprotective and immunomodulatory properties, and ligand for all high-affinity neurotrophin tyrosine kinase receptors (Trk), also exerts important effects on hyperalgesia. Its synthetic, 17-spiro-epoxy analogue, BNN27,...

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Detalles Bibliográficos
Autores principales: Poulaki, Smaragda, Rassouli, Olga, Liapakis, George, Gravanis, Achille, Venihaki, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469064/
https://www.ncbi.nlm.nih.gov/pubmed/34572370
http://dx.doi.org/10.3390/biomedicines9091185