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Star-PAP RNA Binding Landscape Reveals Novel Role of Star-PAP in mRNA Metabolism That Requires RBM10-RNA Association

Star-PAP is a non-canonical poly(A) polymerase that selects mRNA targets for polyadenylation. Yet, genome-wide direct Star-PAP targets or the mechanism of specific mRNA recognition is still vague. Here, we employ HITS-CLIP to map the cellular Star-PAP binding landscape and the mechanism of global St...

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Detalles Bibliográficos
Autores principales: Koshre, Ganesh R., Shaji, Feba, Mohanan, Neeraja K., Mohan, Nimmy, Ali, Jamshaid, Laishram, Rakesh S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469156/
https://www.ncbi.nlm.nih.gov/pubmed/34576144
http://dx.doi.org/10.3390/ijms22189980