Design, Synthesis, and Cytotoxicity Assessment of [(64)Cu]Cu-NOTA-Terpyridine Platinum Conjugate: A Novel Chemoradiotherapeutic Agent with Flexible Linker

Maximum benefits of chemoradiation therapy with platinum-based compounds are expected if the radiation and the drug are localized simultaneously in cancer cells. To optimize this concomitant effect, we developed the novel chemoradiotherapeutic agent [(64)Cu]Cu-NOTA-C3-TP by conjugating, via a short...

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Detalles Bibliográficos
Autores principales: Khosravifarsani, Meysam, Ait-Mohand, Samia, Paquette, Benoit, Sanche, Léon, Guérin, Brigitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469169/
https://www.ncbi.nlm.nih.gov/pubmed/34578470
http://dx.doi.org/10.3390/nano11092154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469169/
https://www.ncbi.nlm.nih.gov/pubmed/34578470
http://dx.doi.org/10.3390/nano11092154

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