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Characterization of Mono- and Bi-Transgenic Pig-Derived Epidermal Keratinocytes Expressing Human FUT2 and GLA Genes—In Vitro Studies

Pig-to-human xenotransplantation seems to be the response to the contemporary shortage of tissue/organ donors. Unfortunately, the phylogenetic distance between pig and human implies hyperacute xenograft rejection. In this study, we tested the hypothesis that combining expression of human α1,2-fucosy...

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Detalles Bibliográficos
Autores principales: Wiater, Jerzy, Samiec, Marcin, Wartalski, Kamil, Smorąg, Zdzisław, Jura, Jacek, Słomski, Ryszard, Skrzyszowska, Maria, Romek, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469251/
https://www.ncbi.nlm.nih.gov/pubmed/34575846
http://dx.doi.org/10.3390/ijms22189683