Structure-Functional Analysis of Human Cytochrome P450 2C8 Using Directed Evolution

The human genome includes four cytochrome P450 2C subfamily enzymes, and CYP2C8 has generated research interest because it is subject to drug–drug interactions and various polymorphic outcomes. To address the structure-functional complexity of CYP2C8, its catalytic activity was studied using a direc...

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Detalles Bibliográficos
Autores principales: Lee, Rowoon, Kim, Vitchan, Chun, Youngjin, Kim, Donghak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469462/
https://www.ncbi.nlm.nih.gov/pubmed/34575505
http://dx.doi.org/10.3390/pharmaceutics13091429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469462/
https://www.ncbi.nlm.nih.gov/pubmed/34575505
http://dx.doi.org/10.3390/pharmaceutics13091429

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