Necrostatin-1 Prevents Ferroptosis in a RIPK1- and IDO-Independent Manner in Hepatocellular Carcinoma

Ferroptosis is caused by the iron-mediated accumulation of lipid peroxidation, which is distinct from apoptosis and necroptosis. Necrostatin-1 inhibits receptor-interacting serine/threonine-protein kinase 1 (RIPK1) to initiate necroptosis; it also inhibits indoleamine 2,3-dioxygenase (IDO) to regula...

Descripción completa

Detalles Bibliográficos
Autores principales: Yuk, Hanna, Abdullah, Md, Kim, Do-Hyung, Lee, Haeseung, Lee, Seung-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469492/
https://www.ncbi.nlm.nih.gov/pubmed/34572979
http://dx.doi.org/10.3390/antiox10091347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469492/
https://www.ncbi.nlm.nih.gov/pubmed/34572979
http://dx.doi.org/10.3390/antiox10091347

Ejemplares similares