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Necrostatin-1 Prevents Ferroptosis in a RIPK1- and IDO-Independent Manner in Hepatocellular Carcinoma

Ferroptosis is caused by the iron-mediated accumulation of lipid peroxidation, which is distinct from apoptosis and necroptosis. Necrostatin-1 inhibits receptor-interacting serine/threonine-protein kinase 1 (RIPK1) to initiate necroptosis; it also inhibits indoleamine 2,3-dioxygenase (IDO) to regula...

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Detalles Bibliográficos
Autores principales:	Yuk, Hanna, Abdullah, Md, Kim, Do-Hyung, Lee, Haeseung, Lee, Seung-Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469492/ https://www.ncbi.nlm.nih.gov/pubmed/34572979 http://dx.doi.org/10.3390/antiox10091347

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