Design, Synthesis, and Biochemical Evaluation of New Triazole Derivatives as Aurora-A Kinase Inhibitors

Aurora-A kinase, a key mitosis regulator, is expressed in a cell cycle-dependent manner and has an essential role in maintaining chromosomal stability and the normal progression of the cell through mitosis. Aurora-A kinase is overexpressed in many malignant solid tumors, such as breast, ovarian, col...

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Detalles Bibliográficos
Autor principal: Abdullah, Omeima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469531/
https://www.ncbi.nlm.nih.gov/pubmed/34577149
http://dx.doi.org/10.3390/molecules26185678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469531/
https://www.ncbi.nlm.nih.gov/pubmed/34577149
http://dx.doi.org/10.3390/molecules26185678

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