Hematopoietic Prostaglandin D Synthase Inhibitor PK007 Decreases Muscle Necrosis in DMD mdx Model Mice

Duchenne muscular dystrophy (DMD) is characterized by progressive muscle weakness and wasting due to the lack of dystrophin protein. The acute phase of DMD is characterized by muscle necrosis and increased levels of the pro-inflammatory mediator, prostaglandin D2 (PGD2). Inhibiting the production of...

Descripción completa

Detalles Bibliográficos
Autores principales: Yarlagadda, Sai, Kulis, Christina, Noakes, Peter G., Smythe, Mark L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469723/
https://www.ncbi.nlm.nih.gov/pubmed/34575143
http://dx.doi.org/10.3390/life11090994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469723/
https://www.ncbi.nlm.nih.gov/pubmed/34575143
http://dx.doi.org/10.3390/life11090994

Ejemplares similares