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Bone Marrow Ts65Dn Trisomy-Induced Changes in Platelet Functionality and Lymphocytopenia Do Not Impact Atherosclerosis Susceptibility in Mice

The genetic disorder Down syndrome is associated with a decreased susceptibility for atherosclerotic cardiovascular disease. Hematological and immune abnormalities occur frequently in Down syndrome patients. We evaluated, in a preclinical setting, the impact of a Down syndrome-like hematological/imm...

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Detalles Bibliográficos
Autores principales: Korporaal, Suzanne J. A., van der Sluis, Ronald J., Van Eck, Miranda, Hoekstra, Menno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469845/
https://www.ncbi.nlm.nih.gov/pubmed/34564128
http://dx.doi.org/10.3390/jcdd8090110