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Bone Marrow Ts65Dn Trisomy-Induced Changes in Platelet Functionality and Lymphocytopenia Do Not Impact Atherosclerosis Susceptibility in Mice
The genetic disorder Down syndrome is associated with a decreased susceptibility for atherosclerotic cardiovascular disease. Hematological and immune abnormalities occur frequently in Down syndrome patients. We evaluated, in a preclinical setting, the impact of a Down syndrome-like hematological/imm...
Autores principales: | Korporaal, Suzanne J. A., van der Sluis, Ronald J., Van Eck, Miranda, Hoekstra, Menno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469845/ https://www.ncbi.nlm.nih.gov/pubmed/34564128 http://dx.doi.org/10.3390/jcdd8090110 |
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