Naproxen Based 1,3,4-Oxadiazole Derivatives as EGFR Inhibitors: Design, Synthesis, Anticancer, and Computational Studies

A library of novel naproxen based 1,3,4-oxadiazole derivatives (8–16 and 19–26) has been synthesized and screened for cytotoxicity as EGFR inhibitors. Among the synthesized hybrids, compound2-(4-((5-((S)-1-(2-methoxynaphthalen-6-yl)ethyl)-1,3,4-oxadiazol-2-ylthio)methyl)-1H-1,2,3-triazol-1-yl)phenol...

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Detalles Bibliográficos
Autores principales: Alam, Mohammad Mahboob, Nazreen, Syed, Almalki, Abdulraheem S. A., Elhenawy, Ahmed A., Alsenani, Nawaf I., Elbehairi, Serag Eldin I., Malebari, Azizah M., Alfaifi, Mohammad Y., Alsharif, Meshari A., Alfaifi, Sulaiman Y. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469912/
https://www.ncbi.nlm.nih.gov/pubmed/34577570
http://dx.doi.org/10.3390/ph14090870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469912/
https://www.ncbi.nlm.nih.gov/pubmed/34577570
http://dx.doi.org/10.3390/ph14090870

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