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Trehalose Reduces Nerve Injury Induced Nociception in Mice but Negatively Affects Alertness

Trehalose, a sugar from fungi, mimics starvation due to a block of glucose transport and induces Transcription Factor EB- mediated autophagy, likely supported by the upregulation of progranulin. The pro-autophagy effects help to remove pathological proteins and thereby prevent neurodegenerative dise...

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Detalles Bibliográficos
Autores principales: Kraft, Vanessa, Schmitz, Katja, Wilken-Schmitz, Annett, Geisslinger, Gerd, Sisignano, Marco, Tegeder, Irmgard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469914/
https://www.ncbi.nlm.nih.gov/pubmed/34578829
http://dx.doi.org/10.3390/nu13092953