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Trehalose Reduces Nerve Injury Induced Nociception in Mice but Negatively Affects Alertness
Trehalose, a sugar from fungi, mimics starvation due to a block of glucose transport and induces Transcription Factor EB- mediated autophagy, likely supported by the upregulation of progranulin. The pro-autophagy effects help to remove pathological proteins and thereby prevent neurodegenerative dise...
Autores principales: | Kraft, Vanessa, Schmitz, Katja, Wilken-Schmitz, Annett, Geisslinger, Gerd, Sisignano, Marco, Tegeder, Irmgard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469914/ https://www.ncbi.nlm.nih.gov/pubmed/34578829 http://dx.doi.org/10.3390/nu13092953 |
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