Fusion with Promiscuous Gα(16) Subunit Reveals Signaling Bias at Muscarinic Receptors

A complex evaluation of agonist bias at G-protein coupled receptors at the level of G-protein classes and isoforms including non-preferential ones is essential for advanced agonist screening and drug development. Molecular crosstalk in downstream signaling and a lack of sufficiently sensitive and se...

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Detalles Bibliográficos
Autores principales: Randáková, Alena, Nelic, Dominik, Hochmalová, Martina, Zimčík, Pavel, Mulenga, Mutale Jane, Boulos, John, Jakubík, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469978/
https://www.ncbi.nlm.nih.gov/pubmed/34576254
http://dx.doi.org/10.3390/ijms221810089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469978/
https://www.ncbi.nlm.nih.gov/pubmed/34576254
http://dx.doi.org/10.3390/ijms221810089

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