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Fusion with Promiscuous Gα(16) Subunit Reveals Signaling Bias at Muscarinic Receptors
A complex evaluation of agonist bias at G-protein coupled receptors at the level of G-protein classes and isoforms including non-preferential ones is essential for advanced agonist screening and drug development. Molecular crosstalk in downstream signaling and a lack of sufficiently sensitive and se...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469978/ https://www.ncbi.nlm.nih.gov/pubmed/34576254 http://dx.doi.org/10.3390/ijms221810089 |