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Accurate Sequence-Based Prediction of Deleterious nsSNPs with Multiple Sequence Profiles and Putative Binding Residues

Non-synonymous single nucleotide polymorphisms (nsSNPs) may result in pathogenic changes that are associated with human diseases. Accurate prediction of these deleterious nsSNPs is in high demand. The existing predictors of deleterious nsSNPs secure modest levels of predictive performance, leaving r...

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Detalles Bibliográficos
Autores principales: Song, Ruiyang, Cao, Baixin, Peng, Zhenling, Oldfield, Christopher J., Kurgan, Lukasz, Wong, Ka-Chun, Yang, Jianyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469993/
https://www.ncbi.nlm.nih.gov/pubmed/34572550
http://dx.doi.org/10.3390/biom11091337