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Two Antibody-Guided Lactic-co-Glycolic Acid-Polyethylenimine (LGA-PEI) Nanoparticle Delivery Systems for Therapeutic Nucleic Acids

We previously reported a new polymer, lactic-co-glycolic acid-polyethylenimine (LGA-PEI), as an improved nanoparticle (NP) delivery for therapeutic nucleic acids (TNAs). Here, we further developed two antibody (Ab)-conjugated LGA-PEI NP technologies for active-targeting delivery of TNAs. LGA-PEI was...

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Detalles Bibliográficos
Autores principales: Lü, Jian-Ming, Liang, Zhengdong, Liu, Dongliang, Zhan, Bin, Yao, Qizhi, Chen, Changyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470087/
https://www.ncbi.nlm.nih.gov/pubmed/34577541
http://dx.doi.org/10.3390/ph14090841