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Novel Insights into Epigenetic Regulation of IL6 Pathway: In Silico Perspective on Inflammation and Cancer Relationship

IL-6 pathway is abnormally hyperactivated in several cancers triggering tumor cell growth and immune system inhibition. Along with genomic mutation, the IL6 pathway gene expression can be affected by DNA methylation, microRNAs, and post-translational modifications. Computational analysis was perform...

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Detalles Bibliográficos
Autores principales: Candido, Saverio, Tomasello, Barbara Maria Rita, Lavoro, Alessandro, Falzone, Luca, Gattuso, Giuseppe, Libra, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470126/
https://www.ncbi.nlm.nih.gov/pubmed/34576335
http://dx.doi.org/10.3390/ijms221810172