Benzydamine Reverses TMexCD-TOprJ-Mediated High-Level Tigecycline Resistance in Gram-Negative Bacteria

Recently, a novel efflux pump gene cluster called tmexCD1-toprJ1 and its variants have been identified, which undermine the antibacterial activity of tigecycline, one of the last remaining options effective against multidrug-resistant (MDR) Gram-negative bacteria. Herein, we report the potent synerg...

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Detalles Bibliográficos
Autores principales: Tong, Ziwen, Xu, Tianqi, Deng, Tian, Shi, Jingru, Wang, Zhiqiang, Liu, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470189/
https://www.ncbi.nlm.nih.gov/pubmed/34577607
http://dx.doi.org/10.3390/ph14090907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470189/
https://www.ncbi.nlm.nih.gov/pubmed/34577607
http://dx.doi.org/10.3390/ph14090907

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