NLIP and HAD-like Domains of Pah1 and Lipin 1 Phosphatidate Phosphatases Are Essential for Their Catalytic Activities

Saccharomyces cerevisiae Pah1 phosphatidate phosphatase (PAP) catalyzes the dephosphorylation of phosphatidate to yield diacylglycerol, controlling phospholipids and triacylglycerol metabolisms. Pah1 and human Lipin 1 are intrinsically disordered proteins with 56% and 43% unfolded regions, respectiv...

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Detalles Bibliográficos
Autores principales: Hsu, Wei-Hsin, Huang, Yi-Hao, Chen, Pin-Ru, Hsieh, Lu-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470223/
https://www.ncbi.nlm.nih.gov/pubmed/34576941
http://dx.doi.org/10.3390/molecules26185470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470223/
https://www.ncbi.nlm.nih.gov/pubmed/34576941
http://dx.doi.org/10.3390/molecules26185470

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