7S,15R-Dihydroxy-16S,17S-Epoxy-Docosapentaenoic Acid, a Novel DHA Epoxy Derivative, Inhibits Colorectal Cancer Stemness through Repolarization of Tumor-Associated Macrophage Functions and the ROS/STAT3 Signaling Pathway

Colorectal cancer is a highly malignant cancer that is inherently resistant to many chemotherapeutic drugs owing to the complicated tumor-supportive microenvironment (TME). Tumor-associated macrophages (TAM) are known to mediate colorectal cancer metastasis and relapse and are therefore a promising...

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Detalles Bibliográficos
Autores principales: Wang, Lifang, Choi, Hack Sun, Su, Yan, Lee, Binna, Song, Jae Jun, Jang, Yong-Suk, Seo, Jeong-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470250/
https://www.ncbi.nlm.nih.gov/pubmed/34573091
http://dx.doi.org/10.3390/antiox10091459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470250/
https://www.ncbi.nlm.nih.gov/pubmed/34573091
http://dx.doi.org/10.3390/antiox10091459

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