RhoGDI1-Cdc42 Signaling Is Required for PDGF-BB-Induced Phenotypic Transformation of Vascular Smooth Muscle Cells and Neointima Formation

RhoGTPase is involved in PDGF-BB-mediated VSMC phenotypic modulation. RhoGDIs are key factors in regulating RhoGTPase activation. In the present study, we investigated the regulatory effect of RhoGDI1 on the activation of RhoGTPase in VSMC transformation and neointima formation. Western blot and co-...

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Detalles Bibliográficos
Autores principales: Qi, Yan, Liang, Xiuying, Guan, Haijing, Sun, Jingwen, Yao, Wenjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470270/
https://www.ncbi.nlm.nih.gov/pubmed/34572355
http://dx.doi.org/10.3390/biomedicines9091169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470270/
https://www.ncbi.nlm.nih.gov/pubmed/34572355
http://dx.doi.org/10.3390/biomedicines9091169

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