Comprehensive Investigation of Stereoselective Food Drug Interaction Potential of Resveratrol on Nine P450 and Six UGT Isoforms in Human Liver Microsomes

The stereoselectivity of the food drug inhibition potential of resveratrol on cytochrome P450s and uridine 5′-diphosphoglucuronosyl transferases was investigated in human liver microsomes. Resveratrol enantiomers showed stereoselective inhibition of CYP2C9, CYP3A, and UGT1A1. The inhibitions of CYP1...

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Detalles Bibliográficos
Autores principales: Ji, Seung-Bae, Park, So-Young, Bae, Subin, Seo, Hyung-Ju, Kim, Sin-Eun, Lee, Gyung-Min, Wu, Zhexue, Liu, Kwang-Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470274/
https://www.ncbi.nlm.nih.gov/pubmed/34575495
http://dx.doi.org/10.3390/pharmaceutics13091419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470274/
https://www.ncbi.nlm.nih.gov/pubmed/34575495
http://dx.doi.org/10.3390/pharmaceutics13091419

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