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Improvement of Resveratrol Permeation through Sublingual Mucosa: Chemical Permeation Enhancers versus Spray Drying Technique to Obtain Fast-Disintegrating Sublingual Mini-Tablets

Resveratrol (RSV) is a natural polyphenol with several interesting broad-spectrum pharmacological properties. However, it is characterized by poor oral bioavailability, extensive first-pass effect metabolism and low stability. Indeed, RSV could benefit from the advantage of the sublingual route of a...

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Detalles Bibliográficos
Autores principales: Di Prima, Giulia, Angellotti, Giuseppe, Scarpaci, Amalia Giulia, Murgia, Denise, D’agostino, Fabio, Campisi, Giuseppina, De Caro, Viviana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470294/
https://www.ncbi.nlm.nih.gov/pubmed/34575446
http://dx.doi.org/10.3390/pharmaceutics13091370