Curcumin Reverses NNMT-Induced 5-Fluorouracil Resistance via Increasing ROS and Cell Cycle Arrest in Colorectal Cancer Cells

Nicotinamide N-methyltransferase (NNMT) plays multiple roles in improving the aggressiveness of colorectal cancer (CRC) and enhancing resistance to 5-Fluorouracil (5-FU), making it an attractive therapeutic target. Curcumin (Cur) is a promising natural compound, exhibiting multiple antitumor effects...

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Detalles Bibliográficos
Autores principales: Li, Guoli, Fang, Sining, Shao, Xiao, Li, Yejia, Tong, Qingchao, Kong, Beibei, Chen, Lifen, Wang, Yanzhong, Yang, Jun, Yu, Haitao, Xie, Xinyou, Zhang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470329/
https://www.ncbi.nlm.nih.gov/pubmed/34572508
http://dx.doi.org/10.3390/biom11091295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470329/
https://www.ncbi.nlm.nih.gov/pubmed/34572508
http://dx.doi.org/10.3390/biom11091295

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