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Oncogenes, Proto-Oncogenes, and Lineage Restriction of Cancer Stem Cells
In principle, an oncogene is a cellular gene (proto-oncogene) that is dysfunctional, due to mutation and fusion with another gene or overexpression. Generally, oncogenes are viewed as deregulating cell proliferation or suppressing apoptosis in driving cancer. The cancer stem cell theory states that...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470404/ https://www.ncbi.nlm.nih.gov/pubmed/34575830 http://dx.doi.org/10.3390/ijms22189667 |