The Atypical Cyclin-Dependent Kinase 5 (Cdk5) Guards Podocytes from Apoptosis in Glomerular Disease While Being Dispensable for Podocyte Development

Cyclin-dependent kinase 5 (Cdk5) is expressed in terminally differentiated cells, where it drives development, morphogenesis, and survival. Temporal and spatial kinase activity is regulated by specific activators of Cdk5, dependent on the cell type and environmental factors. In the kidney, Cdk5 is e...

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Detalles Bibliográficos
Autores principales: Mangold, Nicole, Pippin, Jeffrey, Unnersjoe-Jess, David, Koehler, Sybille, Shankland, Stuart, Brähler, Sebastian, Schermer, Bernhard, Benzing, Thomas, Brinkkoetter, Paul T., Hagmann, Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470701/
https://www.ncbi.nlm.nih.gov/pubmed/34572114
http://dx.doi.org/10.3390/cells10092464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470701/
https://www.ncbi.nlm.nih.gov/pubmed/34572114
http://dx.doi.org/10.3390/cells10092464

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