Prolyl Hydroxylase Domain-Containing Protein 3 Gene Expression in Chondrocytes Is Not Essential for Bone Development in Mice

We previously showed that conditional disruption of the Phd2 gene in chondrocytes led to a massive increase in long bone trabecular bone mass. Loss of Phd2 gene expression or inhibition of PHD2 activity by a specific inhibitor resulted in a several-fold compensatory increase in Phd3 expression in ch...

Descripción completa

Detalles Bibliográficos
Autores principales: Xing, Weirong, Pourteymoor, Sheila, Gomez, Gustavo A., Chen, Yian, Mohan, Subburaman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470734/
https://www.ncbi.nlm.nih.gov/pubmed/34571849
http://dx.doi.org/10.3390/cells10092200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470734/
https://www.ncbi.nlm.nih.gov/pubmed/34571849
http://dx.doi.org/10.3390/cells10092200

Ejemplares similares