Passive Transfer of Blood Sera from ALS Patients with Identified Mutations Results in Elevated Motoneuronal Calcium Level and Loss of Motor Neurons in the Spinal Cord of Mice

Introduction: Previously, we demonstrated the degeneration of axon terminals in mice after repeated injections of blood sera from amyotrophic lateral sclerosis (ALS) patients with identified mutations. However, whether a similar treatment affects the cell body of motor neurons (MNs) remained unresol...

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Detalles Bibliográficos
Autores principales: Polgár, Tamás F., Meszlényi, Valéria, Nógrádi, Bernát, Körmöczy, Laura, Spisák, Krisztina, Tripolszki, Kornélia, Széll, Márta, Obál, Izabella, Engelhardt, József I., Siklós, László, Patai, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470779/
https://www.ncbi.nlm.nih.gov/pubmed/34576165
http://dx.doi.org/10.3390/ijms22189994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470779/
https://www.ncbi.nlm.nih.gov/pubmed/34576165
http://dx.doi.org/10.3390/ijms22189994

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