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Passive Transfer of Blood Sera from ALS Patients with Identified Mutations Results in Elevated Motoneuronal Calcium Level and Loss of Motor Neurons in the Spinal Cord of Mice
Introduction: Previously, we demonstrated the degeneration of axon terminals in mice after repeated injections of blood sera from amyotrophic lateral sclerosis (ALS) patients with identified mutations. However, whether a similar treatment affects the cell body of motor neurons (MNs) remained unresol...
Autores principales: | Polgár, Tamás F., Meszlényi, Valéria, Nógrádi, Bernát, Körmöczy, Laura, Spisák, Krisztina, Tripolszki, Kornélia, Széll, Márta, Obál, Izabella, Engelhardt, József I., Siklós, László, Patai, Roland |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470779/ https://www.ncbi.nlm.nih.gov/pubmed/34576165 http://dx.doi.org/10.3390/ijms22189994 |
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