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Transcription Factor Homeobox D9 Drives the Malignant Phenotype of HPV18-Positive Cervical Cancer Cells via Binding to the Viral Early Promoter

SIMPLE SUMMARY: Transcription factor homeobox D9 (HOXD9) was previously reported to bind to the P97 promoter of HPV16 to induce viral E6/E7 oncogenes. In this article, we investigated whether HOXD9 regulated the P105 promoter of HPV18 and examined the role of HOXD9 in intracellular signaling of cerv...

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Detalles Bibliográficos
Autores principales: Hayashi, Shigenori, Iwata, Takashi, Imagawa, Ryotaro, Sugawara, Masaki, Chen, Guanliang, Tanimoto, Satoko, Sugawara, Yo, Tanaka, Ikumo, Matsui, Tomoya, Nishio, Hiroshi, Nakamura, Masaru, Katoh, Yuki, Mori, Seiichiro, Kukimoto, Iwao, Aoki, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470817/
https://www.ncbi.nlm.nih.gov/pubmed/34572841
http://dx.doi.org/10.3390/cancers13184613