8-Amino-6-Methoxyquinoline—Tetrazole Hybrids: Impact of Linkers on Antiplasmodial Activity

A new series of compounds was prepared from 6-methoxyquinolin-8-amine or its N-(2-aminoethyl) analogue via Ugi-azide reaction. Their linkers between the quinoline and the tert-butyltetrazole moieties differ in chain length, basicity and substitution. Compounds were tested for their antiplasmodial ac...

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Detalles Bibliográficos
Autores principales: Hochegger, Patrick, Dolensky, Johanna, Seebacher, Werner, Saf, Robert, Kaiser, Marcel, Mäser, Pascal, Weis, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470823/
https://www.ncbi.nlm.nih.gov/pubmed/34577001
http://dx.doi.org/10.3390/molecules26185530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470823/
https://www.ncbi.nlm.nih.gov/pubmed/34577001
http://dx.doi.org/10.3390/molecules26185530

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