Cell-Permeable Succinate Increases Mitochondrial Membrane Potential and Glycolysis in Leigh Syndrome Patient Fibroblasts

Mitochondrial disorders represent a large group of severe genetic disorders mainly impacting organ systems with high energy requirements. Leigh syndrome (LS) is a classic example of a mitochondrial disorder resulting from pathogenic mutations that disrupt oxidative phosphorylation capacities. Curren...

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Detalles Bibliográficos
Autores principales: Bakare, Ajibola B., Rao, Raj R., Iyer, Shilpa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470843/
https://www.ncbi.nlm.nih.gov/pubmed/34571904
http://dx.doi.org/10.3390/cells10092255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470843/
https://www.ncbi.nlm.nih.gov/pubmed/34571904
http://dx.doi.org/10.3390/cells10092255

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