RIOK2 Inhibitor NSC139021 Exerts Anti-Tumor Effects on Glioblastoma via Inducing Skp2-Mediated Cell Cycle Arrest and Apoptosis

Up to now, the chemotherapy approaches for glioblastoma were limited. 1-[2-Thiazolylazo]-2-naphthol (named as NSC139021) was shown to significantly inhibit the proliferation of prostate cancer cells by targeting the atypical protein kinase RIOK2. It is documented that RIOK2 overexpressed in glioblas...

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Detalles Bibliográficos
Autores principales: Yu, Min, Hu, Xiaoyan, Yan, Jingyu, Wang, Ying, Lu, Fei, Chang, Junlei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470931/
https://www.ncbi.nlm.nih.gov/pubmed/34572430
http://dx.doi.org/10.3390/biomedicines9091244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470931/
https://www.ncbi.nlm.nih.gov/pubmed/34572430
http://dx.doi.org/10.3390/biomedicines9091244

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