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Therapeutic Effects of an Anti-sialyl Lewis X Antibody in a Murine Model of Allergic Asthma

Asthma is an allergic disease that causes severe infiltration of leukocytes into the lungs. Leukocyte infiltration is mediated by the binding of sialyl Lewis X (sLe(x)) glycans present on the leukocytes to E-and P-selectins present on the endothelial cells at the sites of inflammation. Here, we foun...

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Detalles Bibliográficos
Autores principales: Xiong, Wei, Liu, Wenxin, Nishida, Shogo, Komiyama, Daichi, Liu, Wei, Hirakawa, Jotaro, Kawashima, Hiroto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471066/
https://www.ncbi.nlm.nih.gov/pubmed/34576124
http://dx.doi.org/10.3390/ijms22189961