Perturbation of TM6SF2 Expression Alters Lipid Metabolism in a Human Liver Cell Line

Non-alcoholic fatty liver disease (NAFLD) is caused by excess lipid accumulation in hepatocytes. Genome-wide association studies have identified a strong association of NAFLD with non-synonymous E167K amino acid mutation in the transmembrane 6 superfamily member 2 (TM6SF2) protein. The E167K mutatio...

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Detalles Bibliográficos
Autores principales: Pant, Asmita, Chen, Yue, Kuppa, Annapurna, Du, Xiaomeng, Halligan, Brian D., Speliotes, Elizabeth K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471112/
https://www.ncbi.nlm.nih.gov/pubmed/34575933
http://dx.doi.org/10.3390/ijms22189758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471112/
https://www.ncbi.nlm.nih.gov/pubmed/34575933
http://dx.doi.org/10.3390/ijms22189758

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