Discovery of a Non-Nucleoside SETD2 Methyltransferase Inhibitor against Acute Myeloid Leukemia

Histone methyltransferases (HMTs) have attracted considerable attention as potential targets for pharmaceutical intervention in various malignant diseases. These enzymes are known for introducing methyl marks at specific locations of histone proteins, creating a complex system that regulates epigene...

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Detalles Bibliográficos
Autores principales: Bajusz, Dávid, Bognár, Zsolt, Ebner, Jessica, Grebien, Florian, Keserű, György M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471172/
https://www.ncbi.nlm.nih.gov/pubmed/34576219
http://dx.doi.org/10.3390/ijms221810055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471172/
https://www.ncbi.nlm.nih.gov/pubmed/34576219
http://dx.doi.org/10.3390/ijms221810055

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