Glucagon Potentiates Insulin Secretion Via β-Cell GCGR at Physiological Concentrations of Glucose

Incretin-potentiated glucose-stimulated insulin secretion (GSIS) is critical to maintaining euglycemia, of which GLP-1 receptor (GLP-1R) on β-cells plays an indispensable role. Recently, α-cell-derived glucagon but not intestine-derived GLP-1 has been proposed as the critical hormone that potentiate...

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Detalles Bibliográficos
Autores principales: Zhang, Yulin, Han, Chengsheng, Zhu, Wenzhen, Yang, Guoyi, Peng, Xiaohong, Mehta, Sohum, Zhang, Jin, Chen, Liangyi, Liu, Yanmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471175/
https://www.ncbi.nlm.nih.gov/pubmed/34572144
http://dx.doi.org/10.3390/cells10092495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471175/
https://www.ncbi.nlm.nih.gov/pubmed/34572144
http://dx.doi.org/10.3390/cells10092495

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