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Glucagon Potentiates Insulin Secretion Via β-Cell GCGR at Physiological Concentrations of Glucose
Incretin-potentiated glucose-stimulated insulin secretion (GSIS) is critical to maintaining euglycemia, of which GLP-1 receptor (GLP-1R) on β-cells plays an indispensable role. Recently, α-cell-derived glucagon but not intestine-derived GLP-1 has been proposed as the critical hormone that potentiate...
Autores principales: | Zhang, Yulin, Han, Chengsheng, Zhu, Wenzhen, Yang, Guoyi, Peng, Xiaohong, Mehta, Sohum, Zhang, Jin, Chen, Liangyi, Liu, Yanmei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471175/ https://www.ncbi.nlm.nih.gov/pubmed/34572144 http://dx.doi.org/10.3390/cells10092495 |
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