Age-Dependent Decrease in Hepatic Geranylgeranoic Acid Content in C3H/HeN Mice and Its Oral Supplementation Prevents Spontaneous Hepatoma

Geranylgeranoic acid (GGA) has been developed as a preventive agent against second primary hepatoma. Recently, GGA was reported to induce cell death in human hepatoma cells via TLR4-mediated pyroptosis. We have reported that GGA is enzymatically biosynthesized from mevalonic acid in human hepatoma-d...

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Detalles Bibliográficos
Autores principales: Tabata, Yuki, Omori, Masahide, Shidoji, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471303/
https://www.ncbi.nlm.nih.gov/pubmed/34564450
http://dx.doi.org/10.3390/metabo11090634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471303/
https://www.ncbi.nlm.nih.gov/pubmed/34564450
http://dx.doi.org/10.3390/metabo11090634

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