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Calmodulin-Dependent Regulation of Overexpressed but Not Endogenous TMEM16A Expressed in Airway Epithelial Cells

Regulation of the Ca(2+)-activated Cl(−) channel TMEM16A by Ca(2+)/calmodulin (CAM) is discussed controversially. In the present study, we compared regulation of TMEM16A by Ca(2+)/calmodulin (holo-CAM), CAM-dependent kinase (CAMKII), and CAM-dependent phosphatase calcineurin in TMEM16A-overexpressin...

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Detalles Bibliográficos
Autores principales: Talbi, Khaoula, Ousingsawat, Jiraporn, Centeio, Raquel, Schreiber, Rainer, Kunzelmann, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471323/
https://www.ncbi.nlm.nih.gov/pubmed/34564540
http://dx.doi.org/10.3390/membranes11090723